⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747861 | 0.82 | IDO1 (0.42) | — | |
| SCHEMBL8748112 | 0.79 | CYP4A11 (0.41) | — | |
| SCHEMBL8747764 | 0.78 | L3MBTL1 (0.37) | — | |
| SCHEMBL8748149 | 0.71 | ALDH1A1 (0.42) | — | |
| SCHEMBL9242678 | 0.70 | LTA4H (0.38) | — | |
| SCHEMBL8747723 | 0.70 | HSD11B1 (0.32) | — | |
| SCHEMBL9247339 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL9243997 | 0.70 | SLC16A3 (0.35) | — | |
| SCHEMBL9251166 | 0.69 | GSK3B (0.43) | — | |
| SCHEMBL8747780 | 0.68 | ALOX5 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |