SCHEMBL874967

SCHEMBL874967

NC(=O)c1cccc(C(=O)N2Cc3cccc(c3)C2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 8/20 0.46
LMNA P02545 3/20 0.44
TSHR P16473 3/20 0.44
MAPK1 P28482 3/20 0.44
HSD17B10 Q99714 1/20 0.44
USP2 O75604 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.42
L3MBTL3 Q96JM7 1/20 0.42
HPGD P15428 2/20 0.41
PLA2G7 Q13093 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HTT P42858 1/20 0.41
PARP10 Q53GL7 2/20 0.41
PARP15 Q460N3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6903862 0.92 PARP1 (0.47) PARP1LMNATSHRMAPK1HSD17B10
SCHEMBL8156659 0.88 PARP10 (0.42) PARP1TSHRHSD17B10MAPTALDH1A1
SCHEMBL2445561 0.87 MEN1 (0.40) PARP1LMNATSHRMAPK1HSD17B10
SCHEMBL692631 0.85 OPRM1 (0.42) PARP1HSD17B10MAPTALDH1A1TP53
SCHEMBL14786240 0.82 ALDH1A1 (0.62) PARP1LMNATSHRMAPK1HSD17B10
SCHEMBL367502 0.79 HPGD (0.65) LMNATSHRMAPK1USP2MAPT
SCHEMBL4560033 0.79 MEN1 (0.43) PARP1LMNATSHRMAPTMEN1
SCHEMBL8848524 0.79 HPGD (0.45) LMNATSHRMAPK1ALDH1A1L3MBTL1
SCHEMBL369227 0.78 HPGD (0.66) LMNATSHRMAPK1USP2MAPT
SCHEMBL538527 0.78 HPGD (0.66) LMNATSHRMAPK1USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114836873-B Gecko bionic nanofiber velvet friction power generation fabric with self-cleaning and self-powering functions and preparation method thereof 南通大学 2024-05-28 CN claimed
CN-117861449-A Composite ultrafiltration membrane and preparation method and application thereof 北京市科学技术研究院资源环境研究所 2024-04-12 CN claimed
CN-116813902-B Poly (m-phenylene isophthalamide) solution, meta-aramid spinning solution and preparation method thereof 清华大学 2024-04-09 CN disclosed
CN-111224042-B Aromatic polyamide porous membrane, preparation method and lithium secondary battery 微宏先进膜公司 2023-12-26 CN disclosed
CN-112154160-B Modified hydrogenated product, method for producing same, resin composition, and various uses thereof 株式会社可乐丽 2023-10-31 CN disclosed
CN-116813902-A Poly (m-phenylene isophthalamide) solution, meta-aramid spinning solution and preparation method thereof 清华大学 2023-09-29 CN disclosed
CN-116710294-A Tire fabric comprising a disheveled weft reinforcement element with low moisture absorption content 米其林集团总公司 2023-09-05 CN disclosed
CN-116490546-A Heat-resistant high-toughness fiber, method for producing same, and heat-resistant high-toughness film 帝人株式会社 2023-07-25 CN disclosed
CN-113678312-B Separator for nonaqueous secondary battery and nonaqueous secondary battery 帝人株式会社 2023-06-30 CN disclosed
CN-115785505-B Low dielectric poly (m-phenylene isophthalamide) film and preparation method thereof 烟台泰和新材高分子新材料研究院有限公司 2023-04-28 CN disclosed
CN-111320868-B Polymer composition with high dielectric constant and low dielectric loss 杜邦聚合物有限公司 2023-02-28 CN disclosed
EP-0735082-A2 Polyphtalamide resin formulations AMOCO CORPORATION (US) 1996-10-02 EP disclosed
US-5436294-A Impact modifiers for improved ductility and rigidity AMOCO CORPORATION (US) 1995-07-25 US disclosed
US-5387645-A Synergistic blend of polyamide, functionalized polyolefin and functionalized styrene blocks and rubber blocks of ethylene, propylene, butylene and pentylene; maleic anhydride-modified AMOCO CORPORATION (US) 1995-02-07 US disclosed
EP-0477757-A2 Polyamide-Poly(aryl ether sulfone)blends AMOCO CORPORATION (US) 1992-04-01 EP disclosed
EP-0477027-A2 Improved polyphthalamide composition AMOCO CORPORATION (US) 1992-03-25 EP disclosed
EP-0086112-B1 PROCESS AND APPARATUS FOR PRODUCING FIBROUS ASSEMBLY TEIJIN LIMITED (JP) 1987-05-20 EP disclosed
US-4526735-A Extruding fiber forming polymer through spinneret having numerous openings, passing through spinneret an electric current to give polymer Joule heat required for cutting polymer TEIJIN LIMITED (JP) 1985-07-02 US disclosed
EP-0086112-A2 Process and apparatus for producing fibrous assembly TEIJIN LIMITED (JP) 1983-08-17 EP disclosed
EP-0007632-A1 Aromatic polyamide composition TEIJIN LIMITED (JP) 1980-02-06 EP disclosed