SCHEMBL4560033

SCHEMBL4560033

NC(=O)CCCCC(=O)N1Cc2cccc(c2)C1.NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PARP1 P09874 9/20 0.39
PARP10 Q53GL7 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
PARP15 Q460N3 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2445561 0.95 MEN1 (0.40) MEN1KMT2APARP1PARP10LMNA
SCHEMBL170540 0.91 LMNA (0.41) MEN1KMT2ALMNAMAPTNPSR1
SCHEMBL28392745 0.90 HDAC3 (0.41) LMNAMAPTNPSR1
SCHEMBL28397359 0.90 HDAC3 (0.41) LMNAMAPTNPSR1
SCHEMBL8848524 0.89 HPGD (0.45) MEN1KMT2ALMNAGAATSHR
SCHEMBL8962572 0.88 LMNA (0.40) LMNAMAPTNPSR1TSHR
SCHEMBL28528392 0.84 ALDH1A1 (0.39) MEN1KMT2ALMNAMAPTNPSR1
SCHEMBL4439473 0.83 HDAC3 (0.37) LMNAMAPTNPSR1TSHR
SCHEMBL692631 0.83 OPRM1 (0.42) MEN1KMT2APARP1PARP10MAPT
SCHEMBL3751631 0.82 HPGD (0.44) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619024-B2 Resin compositions, intercalates, nanocomposites and laminates prepared with aromatic polyamide and polyphenoxy polymers AMCOL INTERNATIONAL CORPORATION (US) 2009-11-17 US claimed
US-20070049680-A1 Resin compositions, intercalates, nanocomposites and laminates prepared with aromatic polyamide and polyphenoxy polymers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-03-01 US claimed
WO-2013058761-A1 WASTE WATER TREATMENT SYSTEM COMPASS WATER SOLUTIONS, INC. (US) 2013-04-25 WO disclosed
US-7619024-B2 Resin compositions, intercalates, nanocomposites and laminates prepared with aromatic polyamide and polyphenoxy polymers AMCOL INTERNATIONAL CORPORATION (US) 2009-11-17 US disclosed
US-20070049680-A1 Resin compositions, intercalates, nanocomposites and laminates prepared with aromatic polyamide and polyphenoxy polymers MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-03-01 US disclosed