SCHEMBL7708325

SCHEMBL7708325

COc1cc[c]c(-c2ccc(Sc3ccccc3)cc2)c1-c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
MAPT P10636 5/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HPGD P15428 1/20 0.33
MAPK14 Q16539 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
PPP1CA P62136 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP12 P39900 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071376 0.86 PDE4B (0.39) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL7708795 0.85 ALDH1A1 (0.30) ALDH1A1HPGD
SCHEMBL11802233 0.81 CYP1A2 (0.41) ALDH1A1MEN1KMT2AL3MBTL1KDM4E
SCHEMBL7705602 0.78 ACHE (0.35) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL7708543 0.77 ALDH1A1 (0.33) ALDH1A1HPGDMAOAMAOBSLC6A4
SCHEMBL7702832 0.76 MGAM (0.46) MAOB
SCHEMBL7708151 0.76 CRHR1 (0.38) ALDH1A1MAPTMEN1KMT2ACA1
SCHEMBL7702845 0.74 PDGFRB (0.38) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL7705593 0.74 TDO2 (0.35) ALDH1A1MAPTMEN1KMT2ASMN1; SMN2
SCHEMBL7707636 0.72 ABCB1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed