SCHEMBL8750417

SCHEMBL8750417

CCc1ccc(COCc2ccc(CC)c(CC)c2)cc1CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.41
BACE1 P56817 1/20 0.37
TSHR P16473 1/20 0.37
SOD1 P00441 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.34
CYP3A4 P08684 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
IDO1 P14902 2/20 0.32
KCNH2 Q12809 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
TRPA1 O75762 1/20 0.32
AKT1 P31749 1/20 0.32
ALDH1A1 P00352 3/20 0.32
NPC1 O15118 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015634 0.84 LMNA (0.41) DHFRBACE1SOD1ALDH1A1TDP1
SCHEMBL8750429 0.84 TRPA1 (0.40) DHFRBACE1SOD1GPR84TRPA1
SCHEMBL9073262 0.83 RXRA (0.37) BACE1TSHRMRGPRX4CYP3A4KCNH2
SCHEMBL444673 0.80 TRPA1 (0.48) DHFRBACE1TRPA1AKT1ALDH1A1
SCHEMBL10902827 0.79 SRC (0.40) DHFRBACE1SOD1CYP3A4GPR84
SCHEMBL10902822 0.79 DHFR (0.37) DHFRBACE1SOD1CYP3A4
SCHEMBL10916484 0.78 DHFR (0.53) DHFRBACE1CYP3A4GRIN2DGRIN3B
Ethylene SCHEMBL27875997 0.76 TRPA1 (0.44) DHFRBACE1TRPA1AKT1ALDH1A1
SCHEMBL4964086 0.76 KDM4E (0.33) TSHRMRGPRX4ALDH1A1
SCHEMBL15760681 0.75 SLC5A2 (0.36) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0523697-B1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS (JP) 1997-04-02 EP disclosed
US-5447901-A Color-developing sheet: base material coated with composition of /a/ multivalent metal-modified salicylic acid resin formed from salicylic acid, a benzyl compound and optional styrene and /b/ analogous resin free of salicylic acid MITSUI TOATSU CHEMICAL, INC. (JP) 1995-09-05 US disclosed
US-5376615-A Pressure sensitive elements containing a salicylic acid resin and a phenolic resin MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1994-12-27 US disclosed
EP-0523697-A1 Color-developing compositions and their use MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-01-20 EP disclosed