Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | SOD1 | P00441 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8750417 | 0.79 | DHFR (0.41) | DHFRSOD1BACE1CYP3A4 | |
| SCHEMBL6949336 | 0.79 | RXRA (0.42) | SOD1 | |
| SCHEMBL10015634 | 0.78 | LMNA (0.41) | DHFRSOD1BACE1 | |
| SCHEMBL9256358 | 0.77 | SOD1 (0.43) | SOD1 | |
| SCHEMBL1828738 | 0.74 | NPC1 (0.36) | — | |
| SCHEMBL9517681 | 0.74 | PTGS2 (0.32) | SOD1 | |
| SCHEMBL3081383 | 0.74 | CYP2A6 (0.46) | — | |
| SCHEMBL444673 | 0.74 | TRPA1 (0.48) | DHFRBACE1 | |
| SCHEMBL5984175 | 0.74 | GABRA1 (0.41) | — | |
| SCHEMBL5256978 | 0.74 | BACE1 (0.40) | DHFRSOD1BACE1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622388-A | POLYPEPTIDES | ARMOUR PHARMACEUTICAL COMPANY (US) | 1986-11-11 | — | — | US | disclosed |