Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916604 | 0.85 | TSHR (0.56) | KMT2AHSD11B1ALDH1A1CA2TSHR | |
| SCHEMBL10743955 | 0.84 | ALDH1A1 (0.44) | KMT2AHSD11B1ALDH1A1CA2TSHR | |
| SCHEMBL10451127 | 0.80 | PSIP1 (0.50) | KMT2AHSD11B1ALDH1A1PAX8CA2 | |
| SCHEMBL31361829 | 0.79 | THRB (0.59) | KMT2AALDH1A1PAX8CA2CYP3A4 | |
| SCHEMBL5673655 | 0.79 | HSD11B1 (0.44) | KMT2AHSD11B1ALDH1A1CA2TSHR | |
| SCHEMBL13423072 | 0.78 | ALDH1A1 (0.42) | KMT2AHSD11B1ALDH1A1CA2TSHR | |
| SCHEMBL5974400 | 0.78 | CA2 (0.53) | KMT2AALDH1A1PAX8CA2TSHR | |
| SCHEMBL6741405 | 0.78 | THRB (0.62) | KMT2AALDH1A1CA2CYP3A4CYP2C9 | |
| SCHEMBL10622485 | 0.76 | ALDH1A1 (0.49) | KMT2AHSD11B1ALDH1A1PAX8TSHR | |
| SCHEMBL426162 | 0.75 | ALDH1A1 (0.52) | KMT2AHSD11B1ALDH1A1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552629-B1 | Reactive dyes | BAYER AG (DE) | 1997-02-26 | — | — | EP | disclosed |
| US-5591834-A | AZO, PHTHALOCYANINE, AND DIOXAZINE DYES FOR COTTON AND POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5532362-A | COLORFAST, HIGH TINCTORIAL STRENGTH | HOECHST CELANESE CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| EP-0515844-B1 | Phenylazo- or naphthylazobenzenes with several reactive groups | BASF AG (DE) | 1995-12-27 | — | — | EP | disclosed |
| US-5276148-A | Phenylazobenzenes or naphthylazobenzenes having a plurality of fiber-reactive groups | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0552629-A2 | Reactive dyes | BAYER AG (DE) | 1993-07-28 | — | — | EP | disclosed |
| EP-0515844-A1 | Phenylazo- or naphthylazobenzenes with several reactive groups | BASF Aktiengesellschaft (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-5118826-A | Colorfastness | CIBA-GEIGY CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0303081-B1 | WATER SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-5055565-A | Fiber-reactive dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |
| US-5021557-A | Copper-containing formazan dye, colorfast blue shades on cellulose | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| US-4818814-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-04 | — | — | US | disclosed |