Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 11/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9523229 | 0.87 | MAPT (0.43) | MAPTRAB9ANPC1POLBEPHX2 | |
| Mivotilate SCHEMBL8752155 | 0.87 | MAPT (0.43) | MAPTRAB9ANPC1POLBEPHX2 | |
| SCHEMBL9673076 | 0.84 | ALDH1A1 (0.45) | MAPTRAB9ANPC1POLBSMN1; SMN2 | |
| SCHEMBL9672609 | 0.81 | ADRA1A (0.55) | ADRA1APDE4DMAPTRAB9ANPC1 | |
| SCHEMBL8752170 | 0.79 | ADRA1A (0.56) | ADRA1APDE4DRAB9ANPC1POLB | |
| SCHEMBL9674202 | 0.78 | ADRA1A (0.55) | ADRA1APDE4DMAPTRAB9ANPC1 | |
| SCHEMBL9673610 | 0.77 | ADRA1A (0.54) | ADRA1APDE4DMAPTRAB9ANPC1 | |
| SCHEMBL9706732 | 0.76 | ADRA1A (0.72) | ADRA1APDE4DSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL13694514 | 0.76 | MAPT (0.55) | MAPTRAB9ANPC1POLBEPHX2 | |
| SCHEMBL9673541 | 0.74 | TSHR (0.56) | ADRA1APDE4DMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766560-A1 | USE OF THIOKETENE DERIVATIVES FOR PREVENTING OR TREATING HEPATITIS B | YUHAN CORPORATION, LTD. (KR) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996033711-A2 | USE OF THIOKETENE DERIVATIVES FOR PREVENTING OR TREATING HEPATITIS B | YUHAN CORPORATION (KR) | 1996-10-31 | — | — | WO | disclosed |
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |