SCHEMBL875682

SCHEMBL875682

CCCCC(N[C]=O)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC15A1 P46059 1/20 0.32
ALDH1A1 P00352 2/20 0.32
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
CA2 P00918 4/20 0.31
CA1 P00915 3/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
ADH7 P40394 1/20 0.31
TSHR P16473 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP3A4 P08684 1/20 0.31
FDPS P14324 1/20 0.31
DNM1 Q05193 2/20 0.31
CTSK P43235 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269774 0.77
SCHEMBL271579 0.77
SCHEMBL9766339 0.76 MEN1 (0.41) ADH1BADH1CADH1AADH4ADH7
SCHEMBL271666 0.75 PLA2G2C (0.35) SLC15A1ALDH1A1DPP7CA2CA1
SCHEMBL5933020 0.74 DNM1 (0.38) SLC15A1ALDH1A1DPP4DPP8DPP9
SCHEMBL18884674 0.72 DNM1 (0.36) SLC15A1ALDH1A1DPP4DPP8DPP9
SCHEMBL6826697 0.72
SCHEMBL17333439 0.71
SCHEMBL271367 0.71 PLA2G2C (0.33) ALDH1A1DPP4DPP8DPP9DPP7
SCHEMBL270409 0.71 ALDH1A1 (0.37) ALDH1A1CA2CA1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2619183-B1 PROCESS FOR PREPARING SUBSTITUTED N-PHENYLHYDROXYLAMINES BASF SE (DE) 2016-12-07 EP disclosed
US-8563748-B2 Process for preparing substituted N-phenylhydroxylamines BASF SE (DE) 2013-10-22 US disclosed
EP-2619183-A1 PROCESS FOR PREPARING SUBSTITUTED N-PHENYLHYDROXYLAMINES BASF SE (DE) 2013-07-31 EP disclosed
US-20130178634-A1 Process for Preparing Substituted N-Phenylhydroxylamines BASF SE (DE) 2013-07-11 US disclosed
WO-2012038392-A1 PROCESS FOR PREPARING SUBSTITUTED N-PHENYLHYDROXYLAMINES BASF SE (DE) 2012-03-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130178634-A1 Process for Preparing Substituted N-Phenylhydroxylamines PAH, HPD, DNPH1 SLC15A1 4145/4885ALDH1A1 418/4885DPP4 1751/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.