Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.94 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL3485786 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL5427605 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL5419812 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL3485493 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL5427521 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL11137195 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL1765130 | 1.00 | DNM1 (0.94) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL332945 | 0.97 | DNM1 (1.00) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL640740 | 0.97 | DNM1 (1.00) | DNM1SLC22A1ALDH1A1TP53CYP3A4 | |
| SCHEMBL332106 | 0.97 | DNM1 (1.00) | DNM1SLC22A1ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4553061-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-05-14 | — | — | EP | disclosed |
| CN-119585234-A | Method for producing fluorine-containing aromatic compound | 大金工业株式会社 | 2025-03-07 | — | — | CN | disclosed |
| CN-119403778-A | Process for producing fluorinated organic compound | 大金工业株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-112020485-B | Process for producing difluoromethylene compound | 大金工业株式会社 | 2023-11-14 | — | — | CN | disclosed |
| EP-4223736-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | Daikin Industries, Ltd. (JP) | 2023-08-09 | — | — | EP | disclosed |
| US-20230242468-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2023-08-03 | — | — | US | disclosed |
| CN-116249686-A | Process for producing fluorinated organic compound | 大金工业株式会社 | 2023-06-09 | — | — | CN | disclosed |
| US-11377407-B2 | Method for producing difluoromethylene compound | DAIKIN INDUSTRIES, LTD. (JP) | 2022-07-05 | — | — | US | disclosed |
| WO-2022071363-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | ダイキン工業株式会社 | 2022-04-07 | — | — | WO | disclosed |
| US-20210363077-A1 | METHOD FOR PRODUCING DIFLUOROMETHYLENE COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2021-11-25 | — | — | US | disclosed |
| EP-1304316-A1 | PROCESSES FOR THE PRODUCTION OF FLUORINATED ORGANIC COMPOUNDS AND FLUORINATING AGENTS | Daikin Industries, Ltd. (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0781752-B1 | Process for preparing fluorine-containing dicarbonyl compound | DAIKIN IND LTD (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5972064-A | USEFUL FOR FERTILIZER COMPOSITIONS | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-26 | — | — | US | disclosed |
| EP-0808297-B1 | USE OF NOT EASILY VOLATILISED PYRAZOL DERIVATIVES WITH HYDROPHILIC GROUPS AS NITRIFICATION INHIBITORS | BASF AG (DE) | 1999-05-12 | — | — | EP | disclosed |
| EP-0799168-A1 | USE OF PYRAZOLE DERIVATIVES WITH HYDROPHOBIC GROUPS AS NITRIFICATION INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-08 | — | — | EP | disclosed |
| EP-0781752-A1 | Process for preparing fluorine-containing dicarbonyl compound | DAIKIN INDUSTRIES, LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |
| US-5569778-A | REACTING DICARBONYL COMPOUND WITH FLUORINE IN HALOGENATED HYDROCARBON OR NITRILE SOLVENT | DAIKIN INDUSTRIES LTD. (JP) | 1996-10-29 | — | — | US | disclosed |
| WO-1996020146-A1 | USE OF PYRAZOLE DERIVATIVES WITH HYDROPHOBIC GROUPS AS NITRIFICATION INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-07-04 | — | — | WO | disclosed |
| EP-0667332-A1 | PROCESS FOR PRODUCING FLUORINATED DICARBONYL COMPOUND | DAIKIN INDUSTRIES, LIMITED (JP) | 1995-08-16 | — | — | EP | disclosed |
| US-4172005-A | Method of etching a semiconductor substrate | TOKYO SHIBAURA ELECTRIC CO., LTD. (JP) | 1979-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242468-A1 | PRODUCTION METHOD FOR FLUORINATED ORGANIC COMPOUND | IPO5, PFAS, FBL | DNM1 1362/4885SLC22A1 4002/4885ALDH1A1 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.