Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | STS | P08842 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759 | 0.85 | SLC6A2 (0.56) | MAPTPLA2G10PLA2G2ASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL3136989 | 0.83 | SLC6A2 (0.54) | MAPTPLA2G10PLA2G2ASMN1; SMN2KMT2A | |
| SCHEMBL7129800 | 0.79 | MAPT (0.80) | L3MBTL1MAPTSRD5A2PLAUSTS | |
| SCHEMBL4430783 | 0.78 | MAPT (0.67) | L3MBTL1MAPTSRD5A2PLAUSTS | |
| SCHEMBL12710374 | 0.78 | L3MBTL1 (0.62) | L3MBTL1MAPTSRD5A2PLAUSTS | |
| SCHEMBL10445018 | 0.77 | ALDH1A1 (0.65) | L3MBTL1MAPTSRD5A2STSNPC1 | |
| SCHEMBL9850669 | 0.76 | L3MBTL1 (0.65) | L3MBTL1MAPTSRD5A2PLAUSTS | |
| SCHEMBL27628014 | 0.76 | MAPT (0.65) | L3MBTL1MAPTSRD5A2PLAUSTS | |
| SCHEMBL2978267 | 0.76 | PLA2G10 (0.63) | L3MBTL1MAPTSRD5A2PLAUSTS | |
| SCHEMBL12090460 | 0.76 | L3MBTL1 (0.56) | L3MBTL1MAPTSRD5A2PLAUSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1179940-C | Novel 1,2-diphenyl-2-propen-1-one derivatives | ������ҩ��ʽ���� | 2004-12-15 | — | — | CN | disclosed |
| CN-1336910-A | Novel 1,2-diphenyl-2-propen-1-one derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-02-20 | — | — | CN | disclosed |
| EP-1142865-A1 | NOVEL 1,2-DIPHENYL-2-PROPEN-1-ONE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |