SCHEMBL8759869

SCHEMBL8759869

Cc1cccc(N(N=C=O)N=C=O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.41
RAB9A P51151 3/20 0.40
NPC1 O15118 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CASP3 P42574 2/20 0.40
SENP8 Q96LD8 2/20 0.40
SENP7 Q9BQF6 2/20 0.40
SENP6 Q9GZR1 2/20 0.40
NSD2 O96028 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
SIGMAR1 Q99720 1/20 0.39
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
JAK2 O60674 1/20 0.39
HTT P42858 1/20 0.39
PAX8 Q06710 1/20 0.39
POLB P06746 1/20 0.39
RECQL P46063 1/20 0.38
HSD17B1 P14061 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112022 0.75 ALDH1A1 (0.42) ACHERAB9ATDP1LMNAALDH1A1
SCHEMBL10012175 0.74 ACHE (0.46) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL14410806 0.74 ACHE (0.46) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL2095098 0.72 ACHE (0.44) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL2967401 0.71 ACHE (0.42) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL3688115 0.69 ALDH1A1 (0.54) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL8906992 0.69 RAB9A (0.49) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL977663 0.69 ACHE (0.58) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL9216436 0.69 RAB9A (0.42) ACHERAB9ANPC1MEN1KMT2A
SCHEMBL28344446 0.68 ALDH1A1 (0.50) ACHERAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0552896-B1 Biodegradable optically active polymers and intermediate oligomers thereof, and process for producing them TAKASAGO PERFUMERY CO LTD (JP) 1997-06-04 EP disclosed
US-5352763-A Polylactone biopolymer TAKASAGO INTERNATIONAL CORPORATION (JP) 1994-10-04 US disclosed
EP-0552896-A1 Biodegradable optically active polymers and intermediate oligomers thereof, and process for producing them Takasago International Corporation (JP) 1993-07-28 EP disclosed