SCHEMBL10012175

SCHEMBL10012175

Cc1cccc(N([C]=O)c2cccc(C)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.46
HSD17B1 P14061 3/20 0.40
HSD17B2 P37059 3/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NSD2 O96028 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
PAX8 Q06710 2/20 0.38
JAK2 O60674 1/20 0.38
HTT P42858 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9216436 0.94 RAB9A (0.42) ACHEHSD17B1HSD17B2NPC1RAB9A
SCHEMBL2095098 0.81 ACHE (0.44) ACHEHSD17B1HSD17B2NPC1RAB9A
SCHEMBL7419938 0.79 TSPO (0.41) ACHENPC1RAB9AMEN1KMT2A
SCHEMBL2967401 0.79 ACHE (0.42) ACHEHSD17B1HSD17B2NPC1RAB9A
SCHEMBL4634298 0.74 CA12 (0.44) ACHENPC1RAB9AMEN1KMT2A
SCHEMBL977663 0.74 ACHE (0.58) ACHEHSD17B1HSD17B2NPC1RAB9A
SCHEMBL8759869 0.74 ACHE (0.41) ACHEHSD17B1HSD17B2NPC1RAB9A
SCHEMBL14471589 0.72 MAOA (0.40) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL12879 0.72 ALDH1A1 (0.56) ACHEHSD17B1HSD17B2NPC1RAB9A
SCHEMBL134721 0.72 ACHE (0.55) ACHEHSD17B1HSD17B2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed