Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155756 | 0.80 | TDP1 (0.56) | L3MBTL1SMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL10340699 | 0.76 | L3MBTL1 (0.69) | L3MBTL1SMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL658106 | 0.76 | MAPT (0.64) | L3MBTL1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL15081877 | 0.76 | NPC1 (0.54) | L3MBTL1SMN1; SMN2GAAALDH1A1NPC1 | |
| SCHEMBL10340675 | 0.75 | L3MBTL1 (0.71) | L3MBTL1SMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL10907809 | 0.74 | RAB9A (0.62) | L3MBTL1SMN1; SMN2GAAALDH1A1KMT2A | |
| SCHEMBL10340733 | 0.74 | L3MBTL1 (0.66) | L3MBTL1SMN1; SMN2GAAMEN1ALDH1A1 | |
| SCHEMBL1832083 | 0.72 | ALOX15 (0.77) | L3MBTL1SMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL1008237 | 0.72 | SMN1; SMN2 (0.51) | L3MBTL1SMN1; SMN2GAAPOLBNPC1 | |
| SCHEMBL1008238 | 0.72 | SMN1; SMN2 (0.51) | L3MBTL1SMN1; SMN2GAAPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0590415-B1 | 1,2,4-Oxadiazole derivatives for controlling endoparasites | BAYER AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0590415-A2 | 1,2,4-Oxadiazole derivatives for controlling endoparasites | BAYER AG (DE) | 1994-04-06 | — | — | EP | disclosed |