Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 16/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074050 | 0.94 | METAP2 (0.45) | GPR88SCN9AMETAP2METAP1 | |
| SCHEMBL17074049 | 0.94 | METAP2 (0.45) | GPR88SCN9AMETAP2METAP1 | |
| SCHEMBL8762366 | 0.90 | KDM4E (0.49) | GPR88SCN9AMETAP2METAP1 | |
| SCHEMBL8649887 | 0.84 | MMP2 (0.49) | GPR88SCN9A | |
| SCHEMBL8761863 | 0.83 | MMP9 (0.57) | POLB | |
| SCHEMBL9116086 | 0.83 | LTA4H (0.45) | — | |
| SCHEMBL8761898 | 0.83 | MMP9 (0.57) | POLB | |
| SCHEMBL8761910 | 0.81 | POLB (0.47) | POLB | |
| SCHEMBL8761933 | 0.79 | DPP4 (0.42) | — | |
| SCHEMBL8760756 | 0.78 | POLB (0.53) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286509-A | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners | THE COCA-COLA COMPANY (US) | 1994-02-15 | — | — | US | claimed |
| EP-0779296-A2 | D-alpha-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as intermediates for artificial sweeteners | THE COCA-COLA COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1995017418-A2 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-α-AMINOALKANOYL-(S)-N-α-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS | THE COCA-COLA COMPANY (US) | 1995-06-29 | — | — | WO | disclosed |
| US-5286509-A | L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners | THE COCA-COLA COMPANY (US) | 1994-02-15 | — | — | US | disclosed |