Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.38 |
| ▸ | MMP12 | P39900 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP16 | P51512 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834739 | 0.87 | HTR6 (0.57) | HTR6KMT2ACA1CA2TSHR | |
| SCHEMBL28609453 | 0.84 | GAA (0.56) | HTR6RAPGEF4KMT2ACA1CA2 | |
| SCHEMBL1682100 | 0.82 | GAA (0.50) | HTR6KMT2ACA1CA2TSHR | |
| SCHEMBL29136610 | 0.80 | HSD11B1 (0.55) | HTR6RAPGEF4KMT2AHSD11B1 | |
| SCHEMBL3835169 | 0.78 | HTR6 (0.70) | HTR6RAPGEF4KMT2AMMP1MMP2 | |
| SCHEMBL896933 | 0.77 | RAPGEF4 (0.56) | HTR6RAPGEF4KMT2AMMP1MMP2 | |
| SCHEMBL3316403 | 0.76 | POLB (0.49) | HTR6RAPGEF4KMT2ACA1CA2 | |
| SCHEMBL9488438 | 0.73 | HTR6 (0.52) | HTR6KMT2ACA1CA2TSHR | |
| SCHEMBL9462475 | 0.72 | RAPGEF4 (0.41) | HTR6RAPGEF4KMT2AMMP1MMP2 | |
| SCHEMBL6916722 | 0.71 | RAD51 (0.38) | HTR6KMT2ACA1CA2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394933-B1 | Polyphenylene sulfide resin composition | TORAY INDUSTRIES (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5488084-A | ALLOY WITH POLYAMIDES, IMPACT RESISTANCE | TORAY INDUSTRIES, INC. (JP) | 1996-01-30 | — | — | US | disclosed |
| EP-0394933-A2 | Polyphenylene sulfide resin composition | TORAY INDUSTRIES, INC. (JP) | 1990-10-31 | — | — | EP | disclosed |