Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14020814 | 0.83 | PTK2 (0.45) | ALDH1A1LMNATSHRNPC1RAB9A | |
| SCHEMBL17148529 | 0.81 | NOTUM (0.47) | ALDH1A1LMNANPC1RAB9AKDM4E | |
| SCHEMBL23291112 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNATSHRNR1H2NR1H3 | |
| SCHEMBL62239 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNANPC1RAB9AKDM4E | |
| SCHEMBL29699566 | 0.79 | HSD11B1 (0.50) | HSD11B1ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3658697 | 0.79 | L3MBTL1 (0.59) | HSD11B1ALDH1A1LMNATSHRNR1H2 | |
| SCHEMBL22575355 | 0.79 | NOTUM (0.45) | HSD11B1LMNANPC1RAB9AKMT2A | |
| SCHEMBL19219072 | 0.78 | L3MBTL1 (0.46) | ALDH1A1LMNAKDM4EKMT2AGAA | |
| SCHEMBL2451213 | 0.78 | L3MBTL1 (0.49) | ALDH1A1LMNAKDM4EKMT2AHSD17B10 | |
| SCHEMBL12297066 | 0.77 | TP53 (0.40) | HSD11B1ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725776-B1 | 3-ARYL-4-ALKYL AND 4,5-DIALKYL-4H-1,2,4-TRIAZOLES USEFUL AS MEMORY ENHANCERS | MERRELL PHARMA INC (US) | 1997-07-16 | — | — | EP | disclosed |