SCHEMBL19219072

SCHEMBL19219072

Cn1cnnc1-c1ccc(-c2ccncc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
MAPK9 P45984 1/20 0.43
MAPK10 P53779 1/20 0.43
MAPT P10636 2/20 0.42
LMNA P02545 1/20 0.42
KIF11 P52732 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPK14 Q16539 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
GAA P10253 1/20 0.38
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
AURKA O14965 1/20 0.38
TTK P33981 1/20 0.38
AURKB Q96GD4 1/20 0.38
INCENP Q9NQS7 1/20 0.38
NSD3 Q9BZ95 1/20 0.38
CYP1A2 P05177 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2451213 0.96 L3MBTL1 (0.49) L3MBTL1MAPK9MAPK10MAPTLMNA
SCHEMBL14020814 0.82 PTK2 (0.45) L3MBTL1MAPTLMNASMN1; SMN2MEN1
SCHEMBL23291112 0.78 ALDH1A1 (0.44) L3MBTL1MAPTLMNASMN1; SMN2MEN1
SCHEMBL8763523 0.78 HSD11B1 (0.45) LMNASMN1; SMN2KMT2AGAAALDH1A1
SCHEMBL62239 0.78 ALDH1A1 (0.42) L3MBTL1LMNASMN1; SMN2GAAALDH1A1
SCHEMBL2477243 0.78 ALDH1A1 (0.47) L3MBTL1MAPTLMNASMN1; SMN2MEN1
SCHEMBL3658697 0.78 L3MBTL1 (0.59) L3MBTL1LMNASMN1; SMN2KMT2AGAA
SCHEMBL21408693 0.77 PCSK9 (0.37) L3MBTL1MAPK9MAPK10LMNASMN1; SMN2
SCHEMBL22143988 0.76 PTK2 (0.42) L3MBTL1MAPTLMNAKIF11SMN1; SMN2
SCHEMBL12297066 0.76 TP53 (0.40) L3MBTL1MAPTSMN1; SMN2KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9932522-B2 Electrochromic compound, electrochromic composition, display element, and dimming element RICOH COMPANY, LTD. (JP) 2018-04-03 US disclosed
US-9932522-B2 Electrochromic compound, electrochromic composition, display element, and dimming element RICOH COMPANY, LTD. (JP) 2018-04-03 US disclosed
US-20170226413-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-10 US disclosed
US-20170226413-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170226413-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, DISPLAY ELEMENT, AND DIMMING ELEMENT EMC2, EMC1, KCNB2 L3MBTL1 3136/4885MAPK9 3509/4885MAPK10 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.