Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19219072 | 0.96 | L3MBTL1 (0.46) | L3MBTL1MAPK9MAPK10GAAMEN1 | |
| SCHEMBL14020814 | 0.81 | PTK2 (0.45) | L3MBTL1MEN1KMT2ALMNAMAPT | |
| SCHEMBL3658697 | 0.81 | L3MBTL1 (0.59) | L3MBTL1GAAKMT2ALMNAALDH1A1 | |
| SCHEMBL21408693 | 0.80 | PCSK9 (0.37) | L3MBTL1MAPK9MAPK10GAALMNA | |
| SCHEMBL23291112 | 0.78 | ALDH1A1 (0.44) | L3MBTL1GAAMEN1KMT2ALMNA | |
| SCHEMBL61170 | 0.78 | ALDH1A1 (0.38) | L3MBTL1GAALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL62239 | 0.78 | ALDH1A1 (0.42) | L3MBTL1GAALMNAALDH1A1HPGD | |
| SCHEMBL8763523 | 0.78 | HSD11B1 (0.45) | GAAKMT2ALMNAALDH1A1HPGD | |
| SCHEMBL21811859 | 0.77 | CYP2A6 (0.50) | L3MBTL1GAAMEN1KMT2ALMNA | |
| SCHEMBL28660838 | 0.77 | L3MBTL1 (0.46) | L3MBTL1MAPK9MAPK10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110224261-A1 | CRYSTALLINE FORM OF 4-(5--4-METHYL-4H-1,2,4-TRIAZOL-3-YL)PYRIDINE | ASTRAZENECA AB (SE) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224261-A1 | CRYSTALLINE FORM OF 4-(5--4-METHYL-4H-1,2,4-TRIAZOL-3-YL)PYRIDINE | ALPI, PYGL, SI | L3MBTL1 4822/4885MAPK9 4128/4885MAPK10 3976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.