Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4247243 | 0.82 | PLCG1 (0.56) | HSD11B1PLCG1ALDH1A1KMT2AGAA | |
| SCHEMBL8764322 | 0.80 | KMT2A (0.39) | HSD11B1MCL1ALDH1A1KMT2AGAA | |
| SCHEMBL8764391 | 0.79 | HSD11B1 (0.43) | HSD11B1MCL1ALDH1A1KMT2ATSHR | |
| SCHEMBL8763365 | 0.79 | MEN1 (0.49) | HSD11B1PLCG1ALDH1A1KMT2A | |
| SCHEMBL8764306 | 0.76 | CDK1 (0.38) | L3MBTL1 | |
| SCHEMBL8764970 | 0.76 | HTR6 (0.43) | PLCG1 | |
| SCHEMBL30165578 | 0.75 | HSD11B1 (0.51) | HSD11B1MCL1ALDH1A1KMT2AABCC9 | |
| SCHEMBL4433417 | 0.75 | HSD11B1 (0.51) | HSD11B1MCL1ALDH1A1KMT2AABCC9 | |
| SCHEMBL8764400 | 0.73 | PSIP1 (0.50) | HSD11B1PLCG1ALDH1A1KMT2ATSHR | |
| SCHEMBL8765900 | 0.72 | PSIP1 (0.48) | HSD11B1ALDH1A1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5596122-A | INSECTICIDES AND LARVICIDES | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |