Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21216562 | 0.83 | HTR6 (0.48) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL2378222 | 0.81 | HTR6 (0.44) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL4074736 | 0.78 | SLC22A12 (0.49) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL3528957 | 0.77 | ELANE (0.60) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL6972429 | 0.77 | ALPL (0.47) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL14488968 | 0.76 | HTR6 (0.44) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL8764342 | 0.76 | HSD11B1 (0.45) | PLCG1 | |
| SCHEMBL8763365 | 0.76 | MEN1 (0.49) | SLC22A12PLCG1 | |
| SCHEMBL645001 | 0.75 | ALPL (0.46) | HTR6ALPLSLC22A12SLC40A1BRD4 | |
| SCHEMBL2646108 | 0.75 | ALPL (0.46) | HTR6ALPLSLC22A12SLC40A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | claimed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | claimed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | claimed |