Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764342 | 0.80 | HSD11B1 (0.45) | KMT2AMCL1HSD11B1ALDH1A1GAA | |
| SCHEMBL8763313 | 0.76 | — | — | |
| SCHEMBL8764352 | 0.72 | NPC1 (0.46) | KMT2AHSD11B1ALDH1A1MEN1CYP3A4 | |
| SCHEMBL8764409 | 0.71 | ALDH1A1 (0.41) | KMT2AHSD11B1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL13911244 | 0.71 | CXCR2 (0.49) | KMT2APOLBHSD11B1ALDH1A1MEN1 | |
| SCHEMBL8764400 | 0.71 | PSIP1 (0.50) | KMT2APOLBHSD11B1ALDH1A1TDP1 | |
| SCHEMBL8764306 | 0.70 | CDK1 (0.38) | — | |
| SCHEMBL8764391 | 0.70 | HSD11B1 (0.43) | KMT2AMCL1HSD11B1ALDH1A1MEN1 | |
| SCHEMBL8763338 | 0.69 | SOS1 (0.41) | KMT2AMEN1EPAS1TP53 | |
| SCHEMBL8764348 | 0.68 | SOD1 (0.41) | EPAS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5596122-A | INSECTICIDES AND LARVICIDES | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |