Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764978 | 0.84 | RECQL (0.46) | CYP3A4CA1CA2L3MBTL1KMT2A | |
| SCHEMBL8763331 | 0.82 | ALDH1A1 (0.43) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8763338 | 0.81 | SOS1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3254088 | 0.81 | ALDH1A1 (0.59) | NPC1ALDH1A1CYP3A4MAPK1PSEN1 | |
| SCHEMBL8764317 | 0.81 | PLCG1 (0.67) | CYP3A4CA1CA2CA12CA5A | |
| SCHEMBL8764344 | 0.81 | MMP1 (0.49) | CA1CA2CA12CA9PLCG1 | |
| SCHEMBL6855152 | 0.81 | ALDH1A1 (0.52) | NPC1ALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL8764348 | 0.81 | SOD1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8764409 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP3A4MAPK1CA2KMT2A | |
| SCHEMBL8764400 | 0.80 | PSIP1 (0.50) | ALDH1A1KDM4ECA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | claimed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | claimed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | claimed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5596122-A | INSECTICIDES AND LARVICIDES | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |