SCHEMBL6855152

SCHEMBL6855152

Cc1ccc(S(=O)(=O)CS(=O)(=O)C(F)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KMT2A Q03164 3/20 0.50
MEN1 O00255 1/20 0.50
GAA P10253 1/20 0.45
CTSK P43235 1/20 0.43
MCHR1 Q99705 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
RECQL P46063 1/20 0.41
NPC1 O15118 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763331 0.82 ALDH1A1 (0.43) ALDH1A1KMT2AMEN1CA1CA2
SCHEMBL63945 0.81 ALDH1A1 (0.67) ALDH1A1CYP3A4CYP2C9CYP2C19KMT2A
SCHEMBL8764317 0.81 PLCG1 (0.67) CYP3A4CYP2C9CYP2C19KMT2ACA12
SCHEMBL8764344 0.81 MMP1 (0.49) KMT2ACA12CA1CA2CA9
SCHEMBL8764352 0.81 NPC1 (0.46) ALDH1A1CYP3A4KMT2AMEN1CA12
SCHEMBL13239545 0.80 MMP13 (0.51) ALDH1A1KMT2AMEN1GAACA1
SCHEMBL8764400 0.80 PSIP1 (0.50) ALDH1A1KMT2ACA12CA1CA2
SCHEMBL8764359 0.77 MAPT (0.46) ALDH1A1CA12CA1CA2CA9
SCHEMBL8763322 0.77 CA1 (0.47) ALDH1A1KMT2AMEN1CA12CA1
SCHEMBL8764385 0.77 MMP2 (0.51) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6783912-B2 POSITIVE OR NEGATIVE AMPLIFICATION SHIPLEY COMPANY, L.L.C. 2004-08-31 US disclosed
US-20020009663-A1 Photoacid generators and photoresists comprising same SHIPLEY COMPANY, L.L.C. 2002-01-24 US disclosed
WO-2001063363-A2 PHOTOACID GENERATORS AND PHOTORESISTS COMPRISING SAME SHIPLEY COMPANY, L.L.C. (US) 2001-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020009663-A1 Photoacid generators and photoresists comprising same GSS, TST, SQOR ALDH1A1 350/4885CYP3A4 1732/4885CYP2C9 2573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.