Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.51 |
| ▸ | MMP9 | P14780 | 10/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL8854311 | 0.94 | MMP2 (0.47) | MMP2MMP9MMP14MMP3MMP13 | |
| SCHEMBL13239545 | 0.83 | MMP13 (0.51) | MMP2MMP9MMP13MMP1 | |
| SCHEMBL14572900 | 0.80 | MMP2 (0.55) | MMP2MMP9MMP14MMP3MMP13 | |
| SCHEMBL9172442 | 0.80 | MMP2 (0.49) | MMP2MMP9MMP14MMP3MMP13 | |
| SCHEMBL2377118 | 0.79 | MMP2 (0.54) | MMP2MMP9MMP14MMP3MMP13 | |
| SCHEMBL8763331 | 0.78 | ALDH1A1 (0.43) | MMP2MMP9MMP14MMP13MMP1 | |
| SCHEMBL21649301 | 0.77 | TP53 (0.56) | MMP2MMP9MMP14MMP3MMP13 | |
| SCHEMBL8764352 | 0.77 | NPC1 (0.46) | MMP2MMP9MMP13MMP1 | |
| SCHEMBL8764317 | 0.77 | PLCG1 (0.67) | MMP2MMP9MMP13TP53MMP1 | |
| SCHEMBL8764344 | 0.77 | MMP1 (0.49) | MMP3BCHEACHEMMP1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | claimed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | claimed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | claimed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | claimed |
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5596122-A | INSECTICIDES AND LARVICIDES | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |