Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764215 | 0.92 | CYP26A1 (0.38) | L3MBTL1 | |
| SCHEMBL8764367 | 0.90 | L3MBTL1 (0.41) | L3MBTL1HSD11B1 | |
| SCHEMBL8764380 | 0.88 | TSHR (0.41) | HSD11B1HPGDSLC1A2MAOB | |
| SCHEMBL8764701 | 0.88 | HSD11B1 (0.37) | HSD11B1 | |
| SCHEMBL8762760 | 0.88 | ALDH1A1 (0.42) | — | |
| SCHEMBL8763626 | 0.87 | GRM2 (0.36) | HSD11B1 | |
| SCHEMBL8762699 | 0.86 | TDP1 (0.41) | L3MBTL1 | |
| SCHEMBL8763747 | 0.86 | PTGS1 (0.39) | ACE | |
| SCHEMBL8763790 | 0.86 | HSD11B1 (0.40) | HSD11B1HPGD | |
| SCHEMBL8762774 | 0.85 | GRM2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774455-A1 | Excitatory amino acid receptor antagonists | ELI LILLY AND COMPANY (US) | 1997-05-21 | — | — | EP | disclosed |