Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 13/20 | 0.45 |
| ▸ | CA2 | P00918 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764409 | 0.83 | ALDH1A1 (0.41) | CA2ALDH1A1MAPK1APEX1 | |
| SCHEMBL8764355 | 0.72 | EPAS1 (0.38) | CA2ALDH1A1MAPK1APEX1 | |
| SCHEMBL8763338 | 0.71 | SOS1 (0.41) | CA2 | |
| SCHEMBL6428363 | 0.69 | CA2 (0.48) | CA1CA2 | |
| SCHEMBL13601374 | 0.68 | MAPK1 (0.48) | ALDH1A1MAPK1APEX1 | |
| SCHEMBL11856294 | 0.68 | ALDH1A1 (0.47) | CA1CA2ALDH1A1MAPK1APEX1 | |
| SCHEMBL7662425 | 0.67 | CA2 (0.52) | CA1CA2 | |
| SCHEMBL9231973 | 0.67 | CA2 (0.52) | CA1CA2 | |
| SCHEMBL17024208 | 0.67 | CA2 (0.46) | CA1CA2 | |
| SCHEMBL8764347 | 0.67 | VCAM1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5596122-A | INSECTICIDES AND LARVICIDES | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |