Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764409 | 0.87 | ALDH1A1 (0.41) | EPAS1KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL8764883 | 0.87 | EPAS1 (0.46) | EPAS1KMT2AMEN1ALDH1A1ESPL1 | |
| SCHEMBL8763338 | 0.76 | SOS1 (0.41) | EPAS1KMT2AMEN1CA2 | |
| SCHEMBL8764952 | 0.72 | CA1 (0.45) | ALDH1A1MAPK1CA2APEX1 | |
| SCHEMBL8764347 | 0.71 | VCAM1 (0.55) | ALDH1A1 | |
| SCHEMBL8764352 | 0.70 | NPC1 (0.46) | KMT2AMEN1ALDH1A1MAPK1HSD11B1 | |
| SCHEMBL11818075 | 0.69 | CA2 (0.43) | EPAS1KMT2ACA2APEX1NFE2L2 | |
| SCHEMBL8764348 | 0.67 | SOD1 (0.41) | EPAS1 | |
| SCHEMBL8764306 | 0.66 | CDK1 (0.38) | CA2 | |
| SCHEMBL6856388 | 0.65 | LMNA (0.49) | ALDH1A1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0606756-B1 | Use of disulfonyl methanes for the control of parasites | LILLY CO ELI (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5637603-A | FORMULATION WHICH PROTECTS VERTEBRATE ANIMALS AGAINST PARASITES | ELI LILLY AND COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| US-5614525-A | ANTHELMINTICS | ELI LILLY AND COMPANY (US) | 1997-03-25 | — | — | US | disclosed |
| US-5596122-A | INSECTICIDES AND LARVICIDES | ELI LILLY AND COMPANY (US) | 1997-01-21 | — | — | US | disclosed |
| US-5449681-A | Administering by mouth or injection; anthelmintics, insecticides | ELI LILLY AND COMPANY (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0606756-A1 | Use of disulfonyl methanes for the control of parasites | ELI LILLY AND COMPANY (US) | 1994-07-20 | — | — | EP | disclosed |