Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822757 | 0.77 | NOS3 (0.63) | NOS3NOS2 | |
| SCHEMBL9474492 | 0.77 | NOS3 (0.63) | TSHRNOS3NOS2 | |
| SCHEMBL6280836 | 0.74 | RECQL (0.48) | TSHRNOS3NOS2 | |
| SCHEMBL7693999 | 0.73 | LOXL2 (0.42) | TSHRNOS3NOS2 | |
| SCHEMBL8764962 | 0.73 | TSHR (0.38) | TSHRNOS3NOS2 | |
| SCHEMBL11816122 | 0.70 | GABRA1 (0.34) | TSHR | |
| SCHEMBL11325805 | 0.68 | LOX (0.47) | TSHRNOS3NOS2 | |
| SCHEMBL9474996 | 0.66 | RECQL (0.37) | — | |
| SCHEMBL8765696 | 0.65 | TSHR (0.35) | TSHR | |
| SCHEMBL8764951 | 0.65 | CYP3A4 (0.32) | TSHRNOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |