SCHEMBL8765451

SCHEMBL8765451

CCC(C(=O)O)C(Cl)(Cl)Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
ALDH1A1 P00352 4/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP1A2 P05177 1/20 0.40
TRPA1 O75762 2/20 0.40
HPGD P15428 2/20 0.39
POLB P06746 2/20 0.39
ALPI P09923 1/20 0.38
PKM P14618 1/20 0.38
PTGS1 P23219 1/20 0.38
XIAP P98170 1/20 0.38
SLC7A5 Q01650 1/20 0.38
RECQL P46063 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
ACE P12821 1/20 0.38
MMP8 P22894 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819687 0.81 TRPA1 (0.51) SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9
SCHEMBL4133307 0.79 CPA1 (0.45) SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9
SCHEMBL1633683 0.78 CYP1A2 (0.44) SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9
Bromide SCHEMBL1634841 0.76 CYP1A2 (0.42) SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9
Butyric Acid SCHEMBL29700570 0.73 TRPA1 (0.44) SMN1; SMN2HIF1AALDH1A1CYP3A4CYP2C9
SCHEMBL5188446 0.73 CHRM1 (0.37)
SCHEMBL9633535 0.72 FFAR3 (0.38) ALDH1A1
SCHEMBL5219757 0.71 CA2 (0.31)
SCHEMBL302771 0.71 CYP1A2 (0.55) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL4377967 0.69 CYP2C19 (0.46) HIF1ACYP2C19CYP1A2ACEKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0612772-B1 Luminiscent copolymers BAYER AG (DE) 1997-06-04 EP disclosed
EP-0612772-A1 Luminiscent copolymers BAYER AG (DE) 1994-08-31 EP disclosed