Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.34 |
| ▸ | METAP1 | P53582 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370607 | 0.79 | CA2 (0.52) | ALDH1A1METAP2METAP1L3MBTL1MMP2 | |
| SCHEMBL909449 | 0.77 | MEN1 (0.44) | KDM4ELMNAKMT2AMEN1GAA | |
| SCHEMBL10354989 | 0.74 | KDM4E (0.32) | ALDH1A1MMP2TSHRKDM4ELMNA | |
| SCHEMBL30046969 | 0.74 | SMN1; SMN2 (0.42) | ALDH1A1TSHRKDM4ELMNAMAPT | |
| SCHEMBL4764441 | 0.74 | SMN1; SMN2 (0.42) | ALDH1A1TSHRKDM4ELMNAMAPT | |
| SCHEMBL11972375 | 0.74 | CA2 (0.37) | ALDH1A1METAP2METAP1L3MBTL1MMP2 | |
| SCHEMBL647472 | 0.73 | — | — | |
| SCHEMBL30013662 | 0.73 | — | — | |
| SCHEMBL8778835 | 0.73 | NAPRT (0.41) | ALDH1A1L3MBTL1MMP2TSHRKDM4E | |
| SCHEMBL8765683 | 0.73 | CTSL (0.33) | ALDH1A1MMP2TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778267-A1 | SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-11 | — | — | EP | disclosed |