Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766901 | 0.81 | OPRM1 (0.42) | OPRM1ACHEHDAC4HSD11B1HSD11B2 | |
| SCHEMBL29531177 | 0.80 | ALDH1A1 (0.42) | OPRM1ACHEHSD11B1CYP2C9CYP2C19 | |
| SCHEMBL8064834 | 0.80 | ALDH1A1 (0.42) | OPRM1ACHEHSD11B1CYP2C9CYP2C19 | |
| SCHEMBL8766307 | 0.78 | HDAC4 (0.38) | HDAC4HSD11B1HSD11B2CYP2C9CYP2C19 | |
| SCHEMBL8609713 | 0.77 | HDAC4 (0.50) | OPRM1ACHEHDAC4HSD11B1HSD11B2 | |
| SCHEMBL8766449 | 0.77 | OPRM1 (0.40) | OPRM1HDAC4HSD11B1HSD11B2CYP2C9 | |
| SCHEMBL8767265 | 0.76 | HDAC4 (0.44) | ACHEHDAC4CYP2C9CYP2C19PDE7A | |
| SCHEMBL8766027 | 0.74 | CHRM1 (0.42) | OPRM1HDAC4CYP2C9CYP2C19TSHR | |
| SCHEMBL8766324 | 0.73 | CHRM1 (0.39) | OPRM1 | |
| SCHEMBL8766538 | 0.73 | ACHE (0.35) | ACHEHDAC4CYP2C9CYP2C19PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0601813-B1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORP (JP) | 1997-08-13 | — | — | EP | disclosed |
| US-5501884-A | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5382688-A | Diamino compounds and their production method | CHISSO CORPORATION (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0601813-A1 | Diamino compounds and their production method and liquid crystal alignment layers using the compounds | CHISSO CORPORATION (JP) | 1994-06-15 | — | — | EP | disclosed |