SCHEMBL8766571

SCHEMBL8766571

O=C(O)c1ccc(C(=O)OCC2CO2)c(CC2CO2)c1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.40
MGLL Q99685 5/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6689312 0.92 DHFR (0.41) DHFRMGLL
SCHEMBL4887674 0.86 DHFR (0.43) DHFRMGLL
SCHEMBL27363176 0.86 ALDH1A1 (0.42)
Methacrylic Acid SCHEMBL27990966 0.86 ALDH1A1 (0.44) DHFRMGLL
SCHEMBL9095061 0.85 CYP3A4 (0.43)
SCHEMBL1144451 0.85 DHFR (0.42) DHFRMGLL
SCHEMBL679935 0.85 KDM4E (0.43) DHFRMGLL
SCHEMBL2493818 0.85 DHFR (0.42) DHFRMGLL
SCHEMBL5379875 0.84 SERPINE1 (0.42) DHFRMGLL
SCHEMBL8849900 0.81 THRB (0.36) DHFRMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449292-B1 Multilayer printed circuit board and production thereof HITACHI LTD (JP) 1997-08-20 EP disclosed