SCHEMBL8766924

SCHEMBL8766924

C=COC(=O)OCCNC(=O)C(=C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23064187 0.86 THRB (0.38) THRBACHE
SCHEMBL7625560 0.79 TSHR (0.52) THRBACHE
SCHEMBL8206803 0.79 ACHE (0.33) ACHE
SCHEMBL94524 0.79 THRB (0.53) THRB
SCHEMBL553241 0.78 ALDH1A1 (0.43) THRBACHE
SCHEMBL16805859 0.78 THRB (0.47) THRBACHE
SCHEMBL284797 0.78 TSHR (0.42) THRB
SCHEMBL8767185 0.77 ACHE (0.32) ACHE
SCHEMBL21577398 0.77 TSHR (0.43)
SCHEMBL23064188 0.77 THRB (0.37) THRBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
WO-2023161325-A1 OPHTHALMIC DEVICES BAUSCH + LOMB IRELAND LIMITED (IE) 2023-08-31 WO disclosed
US-20230266505-A1 OPHTHALMIC DEVICES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-24 US disclosed
US-20230266505-A1 OPHTHALMIC DEVICES JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2023-08-24 US disclosed
EP-0611367-B1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB (US) 1997-06-25 EP disclosed
US-5512205-A BIOMEDICAL ARTICLES, CONTACT LENSES BAUSCH & LOMB INCORPORATED (US) 1996-04-30 US disclosed
US-5449729-A Vinyl monomer and crosslinking agent and acrylates with styrene BAUSCH & LOMB INCORPORATED (US) 1995-09-12 US disclosed
EP-0611367-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. BAUSCH & LOMB (US) 1994-08-24 EP disclosed
US-5310779-A Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials BAUSCH & LOMB INCORPORATED (US) 1994-05-10 US disclosed
WO-1993009084-A1 NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION BAUSCH & LOMB INCORPORATED (US) 1993-05-13 WO disclosed