Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766040 | 0.89 | ALDH1A1 (0.53) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL8766591 | 0.84 | HMGCR (0.48) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL8766028 | 0.80 | LMNA (0.40) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL8766734 | 0.80 | ESRRG (0.41) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL7119728 | 0.80 | GAA (0.41) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL8767384 | 0.76 | NR1H4 (0.45) | ALDH1A1GAALMNAMEN1KMT2A | |
| SCHEMBL8766195 | 0.73 | HMGCR (0.52) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL8766589 | 0.73 | GAA (0.47) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL8616827 | 0.72 | GAA (0.47) | ALDH1A1GAATSHRLMNAMEN1 | |
| SCHEMBL8766181 | 0.72 | GAA (0.50) | ALDH1A1GAATSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |