Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 7/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7122163 | 0.86 | NR1H4 (0.42) | NR1H4ALOX5PTGS1PTGS2RIPK1 | |
| SCHEMBL7119728 | 0.86 | GAA (0.41) | NR1H4ALOX5PTGS2FDPSMEN1 | |
| SCHEMBL8766040 | 0.83 | ALDH1A1 (0.53) | ALOX5PTGS1PTGS2MEN1GAA | |
| SCHEMBL7128467 | 0.80 | ALOX5 (0.46) | NR1H4ALOX5PTGS1PTGS2FDPS | |
| SCHEMBL8766589 | 0.79 | GAA (0.47) | FDPSMEN1GAAKMT2ANR1H2 | |
| SCHEMBL8766635 | 0.78 | NR1H4 (0.43) | NR1H4ALOX5PTGS1PTGS2FDPS | |
| SCHEMBL8616827 | 0.76 | GAA (0.47) | FDPSMEN1GAAKMT2ANR1H2 | |
| SCHEMBL8766964 | 0.76 | ALDH1A1 (0.48) | MEN1GAAKMT2AALDH1A1LMNA | |
| SCHEMBL8766658 | 0.75 | MEN1 (0.46) | FDPSMEN1GAAKMT2ALMNA | |
| SCHEMBL8766760 | 0.74 | MEN1 (0.45) | FDPSMEN1GAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |