Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766577 | 0.83 | HTR2A (0.46) | MAOAMAOBACENPC1RAB9A | |
| SCHEMBL8766658 | 0.70 | MEN1 (0.46) | MAOBLMNAKDM4EGAA | |
| SCHEMBL29679451 | 0.69 | TRPM8 (0.62) | NPC1RAB9ATRPM8TAS1R3TAS1R1 | |
| SCHEMBL8766760 | 0.69 | MEN1 (0.45) | LMNAKDM4EGAA | |
| SCHEMBL8766041 | 0.68 | FDPS (0.42) | SMN1; SMN2LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL20915894 | 0.68 | HPGD (0.57) | NPC1RAB9ATRPM8TAS1R3TAS1R1 | |
| SCHEMBL9126496 | 0.67 | HPGD (0.50) | NPC1RAB9ATRPM8INSRIGF1R | |
| SCHEMBL28490944 | 0.67 | MAOB (0.64) | MAOAMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8604814 | 0.67 | CALM1 (0.70) | MAOAMAOBNPC1RAB9AHTR2A | |
| SCHEMBL26617467 | 0.66 | HPGD (0.57) | MAOAMAOBNPC1RAB9AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |