Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451978 | 0.82 | TRPM8 (0.56) | TRPM8RAB9ANPC1HPGDACHE | |
| SCHEMBL16671524 | 0.80 | TAS1R3 (0.54) | TRPM8RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL24667608 | 0.79 | NPC1 (0.48) | TRPM8RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL6332632 | 0.79 | TRPM8 (0.52) | TRPM8RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL4883851 | 0.78 | HPGD (0.47) | TRPM8RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL2937879 | 0.77 | ALDH1A1 (0.51) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL4064688 | 0.77 | MLYCD (0.67) | RAB9ANPC1HPGDMLYCDALDH1A1 | |
| SCHEMBL30128152 | 0.77 | HPGD (0.54) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL29679416 | 0.77 | HPGD (0.49) | TRPM8RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL16671758 | 0.77 | HPGD (0.49) | TRPM8RAB9ANPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022114808-A1 | NEW SMALL-MOLECULE COMPOUND FOR CONTROLLING ENDOSOMAL TOLL-LIKE RECEPTOR AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES USING SAME | 에스앤케이테라퓨틱스 | 2022-06-02 | — | — | WO | disclosed |