Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766586 | 0.88 | MEN1 (0.43) | MEN1KMT2AGAACYP1A2IDH1 | |
| SCHEMBL8766605 | 0.81 | FDPS (0.41) | MEN1KMT2AGAAFDPSRECQL | |
| SCHEMBL8767353 | 0.77 | MEN1 (0.49) | MEN1KMT2AGAACYP1A2KDM4E | |
| SCHEMBL8766505 | 0.70 | MEN1 (0.39) | MEN1KMT2AGAAFDPSRECQL | |
| SCHEMBL8766589 | 0.70 | GAA (0.47) | MEN1KMT2AGAACYP1A2IDH1 | |
| SCHEMBL8014329 | 0.69 | MEN1 (0.51) | MEN1KMT2AGAACYP1A2IDH1 | |
| SCHEMBL9494809 | 0.69 | MEN1 (0.50) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL7125849 | 0.69 | MEN1 (0.45) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL8766187 | 0.69 | HMGCR (0.46) | MEN1KMT2AGAAFDPSRECQL | |
| SCHEMBL8766148 | 0.69 | HMGCR (0.46) | MEN1KMT2AGAAALDH1A1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |