Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8766589 | 0.88 | GAA (0.47) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL7125849 | 0.86 | MEN1 (0.45) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL8616827 | 0.83 | GAA (0.47) | MEN1KMT2AGAAALDH1A1FDPS | |
| SCHEMBL8766658 | 0.80 | MEN1 (0.46) | MEN1KMT2AGAAFDPSCYP1A2 | |
| SCHEMBL8766760 | 0.79 | MEN1 (0.45) | MEN1KMT2AGAAFDPSCYP1A2 | |
| SCHEMBL8766734 | 0.79 | ESRRG (0.41) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL8766645 | 0.77 | FDPS (0.41) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL8767015 | 0.77 | MEN1 (0.47) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL7117955 | 0.75 | GAA (0.43) | MEN1KMT2AGAAALDH1A1NPSR1 | |
| SCHEMBL7119728 | 0.74 | GAA (0.41) | MEN1KMT2AGAAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559079-B1 | Substituted aminophosphonate derivatives, process for their preparation and pharmaceutical compositions containing them | SYMPHAR SA (CH) | 1997-08-13 | — | — | EP | claimed |