Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12845282 | 0.78 | HSD11B1 (0.33) | ESR1SMN1; SMN2LMNAHSD11B1 | |
| SCHEMBL8767208 | 0.74 | LMNA (0.52) | ESR1SMN1; SMN2LMNAHSD11B1PGR | |
| SCHEMBL25458202 | 0.68 | GRIN2D (0.64) | LMNAHSD11B1PGRMEN1KMT2A | |
| SCHEMBL8766728 | 0.65 | LMNA (0.56) | ESR1SMN1; SMN2LMNAHSD11B1PGR | |
| SCHEMBL16352314 | 0.65 | LMNA (0.56) | ESR1SMN1; SMN2LMNAHSD11B1PGR | |
| SCHEMBL2710493 | 0.64 | ALDH1A1 (0.64) | ESR1SMN1; SMN2LMNAPGRMEN1 | |
| SCHEMBL13952954 | 0.64 | ESR2 (0.40) | SMN1; SMN2MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL27845478 | 0.64 | LMNA (0.61) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4569587 | 0.64 | TEAD4 (0.45) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL16216731 | 0.63 | LMNA (0.52) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065021-A1 | Novel Sulfonic-Acid-Group-Containing Segmented Block Copolymer, Application Thereof, and Method of Manufacturing Novel Block Copolymer | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 2011-03-17 | — | — | US | disclosed |