Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23663105 | 0.76 | ALDH1A1 (0.45) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL688552 | 0.74 | GLA (0.48) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL5307611 | 0.72 | TSHR (0.42) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL5717747 | 0.68 | LMNA (1.00) | LMNAALDH1A1KDM4ETSHRPOLB | |
| SCHEMBL360658 | 0.68 | LMNA (0.53) | LMNAALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL30151141 | 0.68 | LMNA (1.00) | LMNAALDH1A1KDM4ETSHRPOLB | |
| SCHEMBL19199613 | 0.68 | LMNA (0.66) | LMNAALDH1A1KDM4EGABRR1POLB | |
| SCHEMBL21925027 | 0.68 | GLA (0.57) | ALDH1A1MAPTGAAKDM4EALOX15 | |
| SCHEMBL5307615 | 0.67 | MAPT (0.54) | ALDH1A1MAPTGAAKDM4EALOX15 | |
| SCHEMBL829306 | 0.67 | CYP2D6 (0.43) | LMNAALDH1A1MAPTGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |