Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CPN1 | P15169 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264438 | 0.81 | LMNA (0.53) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL19952905 | 0.79 | CES2 (0.47) | LMNACES2CES1MAPK1CPN1 | |
| SCHEMBL3521745 | 0.79 | LMNA (0.47) | LMNACES2CES1MAPK1CPN1 | |
| SCHEMBL21404273 | 0.77 | LMNA (0.45) | LMNACES2CES1MAPK1CPN1 | |
| SCHEMBL27489899 | 0.76 | CES2 (0.47) | LMNACES2CES1MAPK1CPN1 | |
| SCHEMBL27466007 | 0.76 | LMNA (0.47) | LMNACES2CES1MAPK1CPN1 | |
| Methoxymethane SCHEMBL7628233 | 0.76 | LMNA (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL8768830 | 0.76 | KDM4E (0.57) | LMNAALDH1A1KDM4EMAPTCYP3A4 | |
| SCHEMBL17709653 | 0.75 | ALDH1A1 (0.60) | LMNACES2CES1MAPK1ALDH1A1 | |
| Toluene SCHEMBL28775724 | 0.75 | LMNA (0.46) | LMNACES2CES1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792146-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-09-03 | — | — | EP | disclosed |
| WO-1997002028-A1 | INACTIVATION OF PATHOGENS USING HYDROXYMETHYLAMINES | HEMASURE, INC. (US) | 1997-01-23 | — | — | WO | disclosed |