Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CPN1 | P15169 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8150588 | 0.84 | LMNA (0.50) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL5821227 | 0.83 | LMNA (0.49) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL28128581 | 0.81 | CES2 (0.47) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL11383664 | 0.81 | LMNA (0.47) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL19952905 | 0.81 | CES2 (0.47) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL17709653 | 0.81 | ALDH1A1 (0.60) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL387303 | 0.80 | LMNA (0.57) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL8768406 | 0.79 | LMNA (0.45) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL27466007 | 0.78 | LMNA (0.47) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL27489899 | 0.78 | CES2 (0.47) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897088-A | Phenylalanine derivative and the preparation method and application thereof containing N- (2- oxoethyl) benzsulfamide | 山东大学 | 2019-06-18 | — | — | CN | claimed |
| CN-109836477-A | Phenylalanine derivative and the preparation method and application thereof containing benzothiadiazine -3- ketone 1,1- dioxide | 山东大学 | 2019-06-04 | — | — | CN | claimed |
| CN-109824756-A | Contain 4-(benzenesulfonyl) phenylalanine derivative and the preparation method and application thereof of piperazine -2- ketone | 山东大学 | 2019-05-31 | — | — | CN | claimed |
| CN-109928890-A | A kind of preparation method of tolvaptan intermediate 2- methyl -4-N- (2- toluyl) benzoic acid | 重庆常捷医药有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-109824756-A | Contain 4-(benzenesulfonyl) phenylalanine derivative and the preparation method and application thereof of piperazine -2- ketone | 山东大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-109796418-A | Phenylalanine derivative and the preparation method and application thereof containing 4- phenyl -1,2,3- triazole | 山东大学 | 2019-05-24 | — | — | CN | disclosed |
| CN-107433198-A | NMPA gentle Fast back-projection algorithm and Pd@RGO catalyst | 重庆大学 | 2017-12-05 | — | — | CN | disclosed |
| US-7709550-B2 | Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate | FUJIFILM CORPORATION (JP) | 2010-05-04 | — | — | US | disclosed |
| EP-1762599-B1 | Ink composition, inkjet recording method, printed material, process for producing lithographic plate, and lithographic printing plate | FUJIFILM CORP (JP) | 2008-03-05 | — | — | EP | disclosed |
| EP-1762599-A1 | Ink composition, inkjet recording method, printed material, process for producing lithographic plate, and lithographic printing plate | FUJIFILM Corporation (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-20070052790-A1 | Ink composition, inkjet recording method, printed material, process for producing lithographic printing plate, and lithographic printing plate | FUJI PHOTO FILM CO., LTD. | 2007-03-08 | — | — | US | disclosed |
| EP-0799247-B1 | CHITOSAN SALTS AND PROCESS FOR THE PREPARATION THEREOF | KIMBERLY CLARK CO (US) | 2002-07-10 | — | — | EP | disclosed |
| EP-0799247-A2 | CHITOSAN SALTS AND PROCESS FOR THE PREPARATION THEREOF | Kimberly-Clark Worldwide, Inc. (US) | 1997-10-08 | — | — | EP | disclosed |
| US-5599916-A | MIXING A CHITOSAN, WATER AND AN ACID; RECOVERING A WATER-SWELLABLE, WATER-INSOLUBLE CHITOSAN; DISPOSABLE PRODUCTS; DIAPERS; SANITARY NAPKINS | KIMBERLY-CLARK CORPORATION (US) | 1997-02-04 | — | — | US | disclosed |
| WO-1996020015-A2 | CHITOSAN SALTS AND PROCESS FOR THE PREPARATION THEREOF | KIMBERLY-CLARK WORDLWIDE, INC. (US) | 1996-07-04 | — | — | WO | disclosed |