Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.33 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769472 | 0.83 | PGR (0.39) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769791 | 0.82 | SRD5A2 (0.37) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8625707 | 0.78 | PGR (0.55) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL10956200 | 0.73 | PGR (0.51) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769794 | 0.72 | PGR (0.48) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769771 | 0.71 | PGR (0.59) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769113 | 0.70 | PGR (0.48) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769455 | 0.67 | PGR (0.49) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769481 | 0.66 | PGR (0.48) | PGRARMAPTNR3C1CHRM2 | |
| SCHEMBL8769023 | 0.65 | PGR (0.67) | PGRARMAPTNR3C1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785211-A1 | New substituted 19-nor-pregnane derivatives | LABORATOIRE THERAMEX (MC) | 1997-07-23 | — | — | EP | disclosed |