Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769809 | 0.78 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL8769841 | 0.78 | CD274 (0.43) | CD274PDCD1 | |
| SCHEMBL8769176 | 0.73 | CD274 (0.51) | CD274PDCD1 | |
| SCHEMBL8693027 | 0.69 | L3MBTL1 (0.61) | L3MBTL1POLBMAPK1 | |
| SCHEMBL11057216 | 0.69 | CD274 (0.40) | CD274PDCD1L3MBTL1 | |
| SCHEMBL11057211 | 0.69 | CD274 (0.40) | CD274PDCD1L3MBTL1 | |
| SCHEMBL19788562 | 0.69 | CD274 (0.70) | CD274PDCD1 | |
| SCHEMBL16554533 | 0.67 | CD274 (0.67) | CD274PDCD1 | |
| SCHEMBL23513688 | 0.67 | CD274 (0.45) | CD274PDCD1 | |
| SCHEMBL16555331 | 0.66 | CD274 (1.00) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792870-A1 | Process for the preparation of ketoximethers by coupling with boronic acid derivatives | Hoechst Schering AgrEvo GmbH (DE) | 1997-09-03 | — | — | EP | disclosed |