Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769809 | 0.79 | CD274 (0.42) | CD274PDCD1 | |
| SCHEMBL8769173 | 0.78 | CD274 (0.48) | CD274PDCD1 | |
| SCHEMBL8769176 | 0.72 | CD274 (0.51) | CD274EPHX1PDCD1 | |
| SCHEMBL19788528 | 0.68 | CD274 (0.61) | CD274PDCD1 | |
| SCHEMBL29271887 | 0.68 | CD274 (0.63) | CD274PDCD1 | |
| SCHEMBL17898332 | 0.67 | CD274 (0.62) | CD274PDCD1 | |
| SCHEMBL6534828 | 0.67 | LMNA (0.62) | — | |
| SCHEMBL23078795 | 0.66 | CD274 (0.58) | CD274PDCD1 | |
| SCHEMBL11060029 | 0.66 | CD274 (0.45) | CD274PDCD1 | |
| SCHEMBL11060036 | 0.66 | CD274 (0.45) | CD274PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792870-A1 | Process for the preparation of ketoximethers by coupling with boronic acid derivatives | Hoechst Schering AgrEvo GmbH (DE) | 1997-09-03 | — | — | EP | disclosed |