Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23639272 | 0.84 | MMP12 (0.51) | ALDH1A1MAPTLMNA | |
| SCHEMBL31579542 | 0.82 | MMP13 (0.56) | MAPTLMNATNKS2MMP13PPARG | |
| SCHEMBL395878 | 0.78 | TDP1 (0.66) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL19955179 | 0.78 | TDP1 (0.66) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL31738422 | 0.78 | TDP1 (0.66) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL5207455 | 0.77 | MAOB (0.56) | MAPTLMNATNKS2MMP13MAOB | |
| SCHEMBL14467187 | 0.77 | ALDH1A1 (0.76) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL31312297 | 0.77 | ALDH1A1 (0.76) | ALDH1A1MAPTLMNATP53TDP1 | |
| SCHEMBL13527924 | 0.76 | TDP1 (0.80) | ALDH1A1MAPTLMNAHPGDTP53 | |
| SCHEMBL8182443 | 0.75 | CRBN (0.67) | MAPTLMNAMMP13MAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647630-B1 | Process for producing 5-arylhydantoins | SHOWA DENKO KK (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5606071-A | Process for preparing 5-arylhydantoins using 5-hydantoin, a halogenating agent and p-phenol | SHOWA DENKO K.K. (JP) | 1997-02-25 | — | — | US | disclosed |
| EP-0647630-A1 | Process for producing 5-arylhydantoins | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1995-04-12 | — | — | EP | disclosed |