SCHEMBL8769557

SCHEMBL8769557

C=CCCC[SiH](C)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
USP2 O75604 1/20 0.33
HPGD P15428 1/20 0.33
TLR8 Q9NR97 1/20 0.31
ACHE P22303 1/20 0.31
LMNA P02545 1/20 0.31
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8770165 0.88 ALDH1A1 (0.33) ALDH1A1L3MBTL1TSHRACHEIDH1
SCHEMBL15134985 0.80 ALDH1A1 (0.36) ALDH1A1L3MBTL1TSHRTDP1USP2
SCHEMBL14956287 0.77 ALDH1A1 (0.35) ALDH1A1L3MBTL1TSHRTDP1USP2
SCHEMBL7815018 0.75 LTA4H (0.36) TSHRTDP1
SCHEMBL8992328 0.75 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL14918714 0.74 ALDH1A1 (0.37) ALDH1A1L3MBTL1TSHRTDP1USP2
SCHEMBL27458860 0.74 TSHR (0.37) ALDH1A1TSHRTDP1LMNA
SCHEMBL6268170 0.74 LTA4H (0.37)
SCHEMBL5681511 0.74 MAOA (0.40)
SCHEMBL9514224 0.74 KCNA3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604401-B1 Production of a catalyst component for producing crystalline polymers CHISSO CORP (JP) 1997-09-24 EP disclosed
EP-0395391-B1 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0564004-B1 A highly stereoregular polypropylene CHISSO CORP (JP) 1996-09-25 EP disclosed
EP-0404519-B1 A process for producing a high-stiffness polypropylene CHISSO CORP (JP) 1996-08-07 EP disclosed
EP-0604401-A2 Production of a catalyst component for producing crystalline polymers CHISSO CORPORATION (JP) 1994-06-29 EP disclosed
EP-0564004-A1 A highly stereoregular polypropylene CHISSO CORPORATION (JP) 1993-10-06 EP disclosed
US-5173540-A Coordination catalyst comprising titanium compound, organo aluminum compound electron donor and a polymer support; transparent, voidless films produced CHISSO CORPORATION (JP) 1992-12-22 US disclosed
US-5077341-A Using coordination catalyst CHISSO CORPORATION (JP) 1991-12-31 US disclosed
EP-0404519-A2 A process for producing a high-stiffness polypropylene CHISSO CORPORATION (JP) 1990-12-27 EP disclosed
EP-0395391-A2 Catalyst component for producing crystalline polymers and a process for producing the catalyst CHISSO CORPORATION (JP) 1990-10-31 EP disclosed