Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 13/20 | 0.51 |
| ▸ | MMP9 | P14780 | 13/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL876861 | 0.89 | MMP2 (0.55) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL876986 | 0.89 | CA1 (0.44) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL877277 | 0.88 | MMP2 (0.49) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL876385 | 0.86 | MMP2 (0.59) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL877131 | 0.83 | MMP2 (0.64) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL877176 | 0.78 | MMP2 (0.48) | MMP2MMP9MMP3MMP13 | |
| SCHEMBL874167 | 0.76 | LPAR1 (0.49) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL877694 | 0.75 | MMP2 (0.47) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL877706 | 0.75 | MMP2 (0.45) | MMP2MMP9MMP3MMP13ALDH1A1 | |
| SCHEMBL874425 | 0.74 | MMP2 (0.48) | MMP2MMP9MMP3MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |